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Inhibitors

Name:  [2-[[5-Chloro-2-(3-morpholin-4-ylanilino)pyrimidin-4-yl]amino]phenyl] prop-2-enoate

Formula:  C23H22ClN5O3

Similarity:  0.8415841584158416

Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  | Dual specificity mitogen-activated protein kinase kinase 1  |

Name:  [2-[[5-Chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]phenyl] prop-2-enoate

Formula:  C24H25ClN6O2

Similarity:  0.8076923076923077

Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  | Dual specificity mitogen-activated protein kinase kinase 1  |

Name:  N-[3-[[[5-Chloro-2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]amino]methyl]phenyl]prop-2-enamide

Formula:  C24H25ClN6O2

Similarity:  0.6578947368421053

Relative Targets:   Tyrosine-protein kinase JAK1  | Dual specificity protein kinase TTK  | Tyrosine-protein kinase JAK3  |

Name:  [2-[[2-[3-(4-Acetylpiperazin-1-yl)anilino]-5-chloropyrimidin-4-yl]amino]phenyl] prop-2-enoate

Formula:  C25H25ClN6O3

Similarity:  0.6495726495726496

Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  | Dual specificity mitogen-activated protein kinase kinase 1  |

Name:  N-[2-[[5-Chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide

Formula:  C24H26ClN7O

Similarity:  0.6491228070175439

Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  | Dual specificity mitogen-activated protein kinase kinase 1  |

Name:  N-[2-[[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide

Formula:  C24H26ClN7O

Similarity:  0.6491228070175439

Relative Targets:   Proto-oncogene tyrosine-protein kinase Src  |

Name:  N-[2-[[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide

Formula:  C24H26ClN7O

Similarity:  0.6491228070175439

Relative Targets:   Nuclear receptor subfamily 2 group C member 2  |

Name:  [2-[[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]phenyl] prop-2-enoate

Formula:  C25H27ClN6O3

Similarity:  0.6218487394957983

Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  |

Name:  2-[[5-chloro-2-(2-methoxy-4-morpholino-anilino)pyrimidin-4-yl]amino]-N-methyl-benzamide

Formula:  C23H25ClN6O3

Similarity:  0.6206896551724138

Relative Targets:   Focal adhesion kinase 1  |

Name:  N-[2-[5-Chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C24H25ClN6O2

Similarity:  0.6068376068376068

Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  | Dual specificity mitogen-activated protein kinase kinase 1  |

Name:  N-[3-[[5-methylsulfanyl-2-(4-morpholinoanilino)pyrimidin-4-yl]amino]phenyl]prop-2-enamide

Formula:  C24H26N6O2S

Similarity:  0.6016949152542372

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  methyl-[2-(4-morpholinoanilino)-4-[3-(prop-2-enoylamino)anilino]pyrimidin-5-yl]-oxido-sulfonium

Formula:  C24H26N6O3S

Similarity:  0.5916666666666667

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  2-[[5-chloro-2-[4-[4-[2-(prop-2-enoylamino)acetyl]piperazin-1-yl]anilino]pyrimidin-4-yl]amino]-N-methyl-benzamide

Formula:  C27H29ClN8O3

Similarity:  0.5692307692307692

Relative Targets:   Focal adhesion kinase 1  |

Name:  N-[2-[5-Chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]sulfanylphenyl]prop-2-enamide

Formula:  C24H25ClN6OS

Similarity:  0.5666666666666667

Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  | Dual specificity mitogen-activated protein kinase kinase 1  |

Name:  2-[[5-chloro-2-[4-[4-[(2R)-2-(prop-2-enoylamino)propanoyl]piperazin-1-yl]anilino]pyrimidin-4-yl]amino]-N-methyl-benzamide

Formula:  C28H31ClN8O3

Similarity:  0.5606060606060606

Relative Targets:   Focal adhesion kinase 1  |

Name:  N-[3-[2-(4-morpholinoanilino)pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C23H23N5O2

Similarity:  0.5603448275862069

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  2-[[5-chloro-2-[4-[4-[3-(prop-2-enoylamino)propanoyl]piperazin-1-yl]anilino]pyrimidin-4-yl]amino]-N-methyl-benzamide

Formula:  C28H31ClN8O3

Similarity:  0.556390977443609

Relative Targets:   Focal adhesion kinase 1  |

Name:  2-Chloro-N-[2-[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]acetamide

Formula:  C23H24Cl2N6O2

Similarity:  0.5537190082644629

Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  |

Name:  N-[2-[5-Methyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C25H28N6O2

Similarity:  0.5537190082644629

Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  | Dual specificity mitogen-activated protein kinase kinase 1  |