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Approved Drugs
Inhibitors
Name:  N-[2-[5-Chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C24H25ClN6O2
Similarity:  0.7699115044247787
Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  | Dual specificity mitogen-activated protein kinase kinase 1  |
Name:  N-[3-[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C24H25ClN6O2
Similarity:  0.7391304347826086
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[2-[5-Methyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C25H28N6O2
Similarity:  0.6949152542372882
Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  | Dual specificity mitogen-activated protein kinase kinase 1  |
Name:  N-[2-[5-Methoxy-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C25H28N6O3
Similarity:  0.6776859504132231
Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  | Dual specificity mitogen-activated protein kinase kinase 1  |
Name:  N-[2-[6-Amino-5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C24H26ClN7O2
Similarity:  0.6557377049180327
Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  | Dual specificity mitogen-activated protein kinase kinase 1  |
Name:  N-[2-[[5-Chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide
Formula:  C24H26ClN7O
Similarity:  0.6528925619834711
Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  | Dual specificity mitogen-activated protein kinase kinase 1  |
Name:  2-Chloro-N-[2-[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]acetamide
Formula:  C23H24Cl2N6O2
Similarity:  0.6528925619834711
Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  |
Name:  N-[3-[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]sulfanylphenyl]prop-2-enamide
Formula:  C24H25ClN6OS
Similarity:  0.6528925619834711
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-bromo-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C24H25BrN6O2
Similarity:  0.6528925619834711
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[2-[[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide
Formula:  C24H26ClN7O
Similarity:  0.6528925619834711
Relative Targets:   Proto-oncogene tyrosine-protein kinase Src  |
Name:  N-[2-[[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide
Formula:  C24H26ClN7O
Similarity:  0.6528925619834711
Relative Targets:   Nuclear receptor subfamily 2 group C member 2  |
Name:  N-[2-[5-Cyclopropyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C27H30N6O2
Similarity:  0.648
Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  | Dual specificity mitogen-activated protein kinase kinase 1  |
Name:  WZ4002
Formula:  C25H27ClN6O3
Similarity:  0.64
Relative Targets:   Epidermal growth factor receptor  | Dipeptidyl peptidase 1  |
Name:  N-[3-[5-chloro-2-[4-(4-methylpiperazine-1-carbonyl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C25H25ClN6O3
Similarity:  0.64
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[2-[5-Chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]sulfanylphenyl]prop-2-enamide
Formula:  C24H25ClN6OS
Similarity:  0.639344262295082
Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  | Dual specificity mitogen-activated protein kinase kinase 1  |
Name:  N-[3-[5-chloro-2-[4-[2-(4-methylpiperazin-1-yl)-2-oxo-ethyl]anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C26H27ClN6O3
Similarity:  0.625
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[2-chloro-3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxy-phenyl]prop-2-enamide
Formula:  C25H26Cl2N6O3
Similarity:  0.6171875
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxy-2-fluoro-phenyl]prop-2-enamide
Formula:  C25H26ClFN6O3
Similarity:  0.6171875
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[2-[4-(4-methylpiperazin-1-yl)anilino]-5-(trifluoromethyl)pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C25H25F3N6O2
Similarity:  0.6171875
Relative Targets:   Epidermal growth factor receptor  |