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Approved Drugs

Name:  Olmutinib

Formula:  C26H26N6O2S

Similarity:  0.5581395348837209

Inhibitors

Name:  N-[2-[[5-Chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide

Formula:  C24H26ClN7O

Similarity:  0.7017543859649122

Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  | Dual specificity mitogen-activated protein kinase kinase 1  |

Name:  N-[2-[5-Chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C24H25ClN6O2

Similarity:  0.7017543859649122

Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  | Dual specificity mitogen-activated protein kinase kinase 1  |

Name:  N-[2-[5-Chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]sulfanylphenyl]prop-2-enamide

Formula:  C24H25ClN6OS

Similarity:  0.7017543859649122

Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  | Dual specificity mitogen-activated protein kinase kinase 1  |

Name:  N-[2-[5-Methyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C25H28N6O2

Similarity:  0.7017543859649122

Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  | Dual specificity mitogen-activated protein kinase kinase 1  |

Name:  N-[2-[[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide

Formula:  C24H26ClN7O

Similarity:  0.7017543859649122

Relative Targets:   Proto-oncogene tyrosine-protein kinase Src  |

Name:  N-[2-[[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide

Formula:  C24H26ClN7O

Similarity:  0.7017543859649122

Relative Targets:   Nuclear receptor subfamily 2 group C member 2  |

Name:  N-[2-[2-[4-(4-Methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C24H26N6O2

Similarity:  0.6991150442477876

Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  | Dual specificity mitogen-activated protein kinase kinase 1  |

Name:  N-[2-[5-Methoxy-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C25H28N6O3

Similarity:  0.6837606837606838

Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  | Dual specificity mitogen-activated protein kinase kinase 1  |

Name:  N-[3-[[2-[4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C28H29N7O2

Similarity:  0.6747967479674797

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[2-[[2-[4-(4-methylpiperazin-1-yl)anilino]-5-(2-thienyl)pyrimidin-4-yl]amino]phenyl]prop-2-enamide

Formula:  C28H29N7OS

Similarity:  0.6693548387096774

Relative Targets:   Proto-oncogene tyrosine-protein kinase Src  |

Name:  N-[2-[[5-(3-furyl)-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide

Formula:  C28H29N7O2

Similarity:  0.6693548387096774

Relative Targets:   Proto-oncogene tyrosine-protein kinase Src  |

Name:  N-[2-[5-Cyclopropyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C27H30N6O2

Similarity:  0.6666666666666666

Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  | Dual specificity mitogen-activated protein kinase kinase 1  |

Name:  [2-[[5-Chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]phenyl] prop-2-enoate

Formula:  C24H25ClN6O2

Similarity:  0.6302521008403361

Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  | Dual specificity mitogen-activated protein kinase kinase 1  |

Name:  N-[2-[[5-(6-methoxy-3-pyridyl)-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide

Formula:  C30H32N8O2

Similarity:  0.6287878787878788

Relative Targets:   Proto-oncogene tyrosine-protein kinase Src  |

Name:  N-[4-[2-[4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C26H26N8O2

Similarity:  0.624

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C26H26N8O2

Similarity:  0.624

Relative Targets:   Epidermal growth factor receptor  | Tyrosine-protein kinase BTK  |

Name:  N-[2-[6-Amino-5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C24H26ClN7O2

Similarity:  0.6198347107438017

Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  | Dual specificity mitogen-activated protein kinase kinase 1  |

Name:  N-[2-[[5-(4-acetylphenyl)-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide

Formula:  C32H33N7O2

Similarity:  0.6194029850746269

Relative Targets:   Proto-oncogene tyrosine-protein kinase Src  |

Name:  N-[3-[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C24H25ClN6O2

Similarity:  0.6166666666666667

Relative Targets:   Epidermal growth factor receptor  |