Searching results

Approved Drugs

Sorry, 0 results found ...

Inhibitors

Name:  N-[2-[5-chloro-2-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C19H19ClN6O3

Similarity:  1.0

Relative Targets:   Nuclear receptor subfamily 2 group C member 2  |

Name:  N-[2-[5-Chloro-2-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C17H15ClN6O2

Similarity:  0.7840909090909091

Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  | Dual specificity mitogen-activated protein kinase kinase 1  |

Name:  N-[2-[5-Chloro-2-[[1-(difluoromethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C17H13ClF2N6O2

Similarity:  0.723404255319149

Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  | Dual specificity mitogen-activated protein kinase kinase 1  |

Name:  N-[2-[5-Chloro-2-[[1-(oxan-4-yl)pyrazol-4-yl]amino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C21H21ClN6O3

Similarity:  0.6476190476190476

Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  | Dual specificity mitogen-activated protein kinase kinase 1  |

Name:  N-[3-[[[5-Chloro-2-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]amino]methyl]phenyl]prop-2-enamide

Formula:  C20H22ClN7O2

Similarity:  0.6407766990291263

Relative Targets:   Aurora kinase A  | Tyrosine-protein kinase JAK1  | Non-receptor tyrosine-protein kinase TYK2  | Dual specificity protein kinase TTK  | Receptor-type tyrosine-protein kinase FLT3  | Tyrosine-protein kinase JAK3  |

Name:  N-[3-[2-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C19H20N6O2

Similarity:  0.5784313725490197

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[4-[2-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C19H20N6O2

Similarity:  0.5631067961165048

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[2-[5-Chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C24H25ClN6O2

Similarity:  0.5478260869565217

Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  | Dual specificity mitogen-activated protein kinase kinase 1  |

Name:  N-[3-[[[5-Chloro-2-[[1-(2-hydroxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]amino]methyl]phenyl]prop-2-enamide

Formula:  C19H20ClN7O2

Similarity:  0.5370370370370371

Relative Targets:   Tyrosine-protein kinase JAK1  | Non-receptor tyrosine-protein kinase TYK2  | Dual specificity protein kinase TTK  | Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[2-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C23H23N7O3

Similarity:  0.5344827586206896

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[3-[[2-[[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-2-fluoro-phenyl]prop-2-enamide

Formula:  C22H23FN8O2

Similarity:  0.5258620689655172

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[6-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C19H20N6O2

Similarity:  0.5188679245283019

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-[4-[6-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]prop-2-enamide

Formula:  C19H20N6O2

Similarity:  0.5046728971962616

Relative Targets:   Tyrosine-protein kinase JAK3  |