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Approved Drugs

Name:  Ibrutinib

Formula:  C25H24N6O2

Similarity:  0.5390625

Inhibitors

Name:  1-[(3R)-3-[[6-(Methylamino)-5-(4-phenoxybenzoyl)pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one

Formula:  C26H27N5O3

Similarity:  0.8952380952380953

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  1-[(3R)-3-[[5-(4-Phenoxybenzoyl)-6-(propan-2-ylamino)pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one

Formula:  C28H31N5O3

Similarity:  0.8545454545454545

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  1-[4-[[6-(Ethylamino)-5-(4-phenoxybenzoyl)pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one

Formula:  C27H29N5O3

Similarity:  0.8532110091743119

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  1-[(3R)-3-[[6-Amino-5-(4-phenoxybenzoyl)pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one

Formula:  C25H25N5O3

Similarity:  0.8317757009345794

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  1-[(3R)-3-[[6-(Dimethylamino)-5-(4-phenoxybenzoyl)pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one

Formula:  C27H29N5O3

Similarity:  0.8108108108108109

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  1-[4-[[6-(Methylamino)-5-(4-phenoxybenzoyl)pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one

Formula:  C26H27N5O3

Similarity:  0.7610619469026548

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  1-[(3R)-3-[[5-(4-Ethoxybenzoyl)-6-(ethylamino)pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one

Formula:  C23H29N5O3

Similarity:  0.7339449541284404

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  1-[4-[[5-(4-Phenoxybenzoyl)-6-(propan-2-ylamino)pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one

Formula:  C28H31N5O3

Similarity:  0.7288135593220338

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  1-[(3R)-3-[[5-(4-Phenoxybenzoyl)-6-piperidin-1-ylpyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one

Formula:  C30H33N5O3

Similarity:  0.7235772357723578

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  1-[4-[6-(Ethylamino)-5-(4-phenoxybenzoyl)pyrimidin-4-yl]piperazin-1-yl]prop-2-en-1-one

Formula:  C26H27N5O3

Similarity:  0.7155172413793104

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  1-[4-[[6-Amino-5-(4-phenoxybenzoyl)pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one

Formula:  C25H25N5O3

Similarity:  0.7043478260869566

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  1-[(3R)-3-[[5-(4-Ethoxybenzoyl)-6-(methylamino)pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one

Formula:  C22H27N5O3

Similarity:  0.6756756756756757

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  1-[(3R)-3-[[6-Amino-5-(4-ethoxybenzoyl)pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one

Formula:  C21H25N5O3

Similarity:  0.6339285714285714

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  1-[4-[6-(Methylamino)-5-(4-phenoxybenzoyl)pyrimidin-4-yl]piperazin-1-yl]prop-2-en-1-one

Formula:  C25H25N5O3

Similarity:  0.6333333333333333

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  1-[4-[[5-(4-Ethoxybenzoyl)-6-(ethylamino)pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one

Formula:  C23H29N5O3

Similarity:  0.6153846153846154

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  1-[4-[5-(4-Phenoxybenzoyl)-6-(propan-2-ylamino)pyrimidin-4-yl]piperazin-1-yl]prop-2-en-1-one

Formula:  C27H29N5O3

Similarity:  0.608

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  1-[4-[6-Amino-5-(4-phenoxybenzoyl)pyrimidin-4-yl]piperazin-1-yl]prop-2-en-1-one

Formula:  C24H23N5O3

Similarity:  0.5950413223140496

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  1-[4-[[5-(4-Ethoxybenzoyl)-6-(methylamino)pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one

Formula:  C22H27N5O3

Similarity:  0.5630252100840336

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  1-[4-[[[6-amino-5-(4-phenoxyphenyl)pyrimidin-4-yl]amino]methyl]-1-piperidyl]prop-2-en-1-one

Formula:  C25H27N5O2

Similarity:  0.552

Relative Targets:   Tyrosine-protein kinase BTK  |