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Approved Drugs
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Inhibitors
Name:  (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-cyclopropylprop-2-enamide
Formula:  C29H30ClN7O3
Similarity:  0.9262295081967213
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-2-cyano-N-(2-hydroxy-1,1-dimethyl-ethyl)-3-[3-(3,4,5-trimethoxyphenyl)-1H-indazol-5-yl]prop-2-enamide
Formula:  C29H30ClN7O3
Similarity:  0.9262295081967213
Relative Targets:   Ribosomal protein S6 kinase alpha-3  |
Name:  (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-4-methylpent-2-enamide
Formula:  C29H32ClN7O3
Similarity:  0.7862595419847328
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-4,4-dimethylpent-2-enamide
Formula:  C30H34ClN7O3
Similarity:  0.7744360902255639
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-3-cyclopropylprop-2-enamide
Formula:  C28H31ClN6O3
Similarity:  0.7557251908396947
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(furan-2-yl)prop-2-enamide
Formula:  C30H28ClN7O4
Similarity:  0.7410071942446043
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(1H-imidazol-5-yl)prop-2-enamide
Formula:  C29H28ClN9O3
Similarity:  0.7410071942446043
Relative Targets:   Epidermal growth factor receptor  |
Name:  WZ4002
Formula:  C25H27ClN6O3
Similarity:  0.7265625
Relative Targets:   Epidermal growth factor receptor  | Dipeptidyl peptidase 1  |
Name:  (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-pyridin-4-ylprop-2-enamide
Formula:  C31H29ClN8O3
Similarity:  0.7253521126760564
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(4-fluorophenyl)prop-2-enamide
Formula:  C32H29ClFN7O3
Similarity:  0.7152777777777778
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(4-methylsulfanylphenyl)prop-2-enamide
Formula:  C33H32ClN7O3S
Similarity:  0.7006802721088435
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(4-cyanophenyl)prop-2-enamide
Formula:  C33H29ClN8O3
Similarity:  0.7006802721088435
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-chloro-2-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)-1-piperidyl]anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C30H36ClN7O3
Similarity:  0.6950354609929078
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(4-nitrophenyl)prop-2-enamide
Formula:  C32H29ClN8O5
Similarity:  0.6912751677852349
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(3-nitrophenyl)prop-2-enamide
Formula:  C32H29ClN8O5
Similarity:  0.6912751677852349
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-[4-(dimethylamino)phenyl]prop-2-enamide
Formula:  C34H35ClN8O3
Similarity:  0.6912751677852349
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-chloro-2-[4-(4-hydroxy-1-piperidyl)-2-methoxy-anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C25H26ClN5O4
Similarity:  0.625
Relative Targets:   Epidermal growth factor receptor  |
Name:  (Z)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-3-(4-fluorophenyl)-2-(trifluoromethyl)prop-2-enamide
Formula:  C32H29ClF4N6O3
Similarity:  0.6193548387096774
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazine-1-carbonyl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C26H27ClN6O4
Similarity:  0.6142857142857143
Relative Targets:   Epidermal growth factor receptor  |