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Inhibitors

Name:  (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-pyridin-4-ylprop-2-enamide

Formula:  C31H29ClN8O3

Similarity:  0.8148148148148148

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(furan-2-yl)prop-2-enamide

Formula:  C30H28ClN7O4

Similarity:  0.8059701492537313

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-4-methylpent-2-enamide

Formula:  C29H32ClN7O3

Similarity:  0.7862595419847328

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-cyclopropylprop-2-enamide

Formula:  C29H30ClN7O3

Similarity:  0.7803030303030303

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-2-cyano-N-(2-hydroxy-1,1-dimethyl-ethyl)-3-[3-(3,4,5-trimethoxyphenyl)-1H-indazol-5-yl]prop-2-enamide

Formula:  C29H30ClN7O3

Similarity:  0.7803030303030303

Relative Targets:   Ribosomal protein S6 kinase alpha-3  |

Name:  (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(4-fluorophenyl)prop-2-enamide

Formula:  C32H29ClFN7O3

Similarity:  0.7769784172661871

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-4,4-dimethylpent-2-enamide

Formula:  C30H34ClN7O3

Similarity:  0.7744360902255639

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(4-methylsulfanylphenyl)prop-2-enamide

Formula:  C33H32ClN7O3S

Similarity:  0.7605633802816901

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(4-cyanophenyl)prop-2-enamide

Formula:  C33H29ClN8O3

Similarity:  0.7605633802816901

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(4-nitrophenyl)prop-2-enamide

Formula:  C32H29ClN8O5

Similarity:  0.75

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(3-nitrophenyl)prop-2-enamide

Formula:  C32H29ClN8O5

Similarity:  0.75

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-[4-(dimethylamino)phenyl]prop-2-enamide

Formula:  C34H35ClN8O3

Similarity:  0.75

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-cyclopentylprop-2-enamide

Formula:  C31H34ClN7O3

Similarity:  0.7410071942446043

Relative Targets:   Epidermal growth factor receptor  |

Name:  WZ4002

Formula:  C25H27ClN6O3

Similarity:  0.7265625

Relative Targets:   Epidermal growth factor receptor  | Dipeptidyl peptidase 1  |

Name:  (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-3-cyclopropylprop-2-enamide

Formula:  C28H31ClN6O3

Similarity:  0.6788321167883211

Relative Targets:   Epidermal growth factor receptor  |

Name:  (Z)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-3-(4-fluorophenyl)-2-(trifluoromethyl)prop-2-enamide

Formula:  C32H29ClF4N6O3

Similarity:  0.6622516556291391

Relative Targets:   Epidermal growth factor receptor  |

Name:  (Z)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-3-(4-methoxyphenyl)-2-(trifluoromethyl)prop-2-enamide

Formula:  C33H32ClF3N6O4

Similarity:  0.6493506493506493

Relative Targets:   Epidermal growth factor receptor  |

Name:  (Z)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-3-[4-(dimethylamino)phenyl]-2-(trifluoromethyl)prop-2-enamide

Formula:  C34H35ClF3N7O3

Similarity:  0.6410256410256411

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxy-5-fluoro-phenyl]prop-2-enamide

Formula:  C25H26ClFN6O3

Similarity:  0.6159420289855072

Relative Targets:   Epidermal growth factor receptor  |