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Approved Drugs
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Inhibitors
Name:  (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(4-fluorophenyl)prop-2-enamide
Formula:  C32H29ClFN7O3
Similarity:  0.8518518518518519
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(4-methylsulfanylphenyl)prop-2-enamide
Formula:  C33H32ClN7O3S
Similarity:  0.8333333333333334
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(4-cyanophenyl)prop-2-enamide
Formula:  C33H29ClN8O3
Similarity:  0.8333333333333334
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(4-nitrophenyl)prop-2-enamide
Formula:  C32H29ClN8O5
Similarity:  0.8214285714285714
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-[4-(dimethylamino)phenyl]prop-2-enamide
Formula:  C34H35ClN8O3
Similarity:  0.8214285714285714
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(furan-2-yl)prop-2-enamide
Formula:  C30H28ClN7O4
Similarity:  0.8148148148148148
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(1H-imidazol-5-yl)prop-2-enamide
Formula:  C29H28ClN9O3
Similarity:  0.8148148148148148
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(3-nitrophenyl)prop-2-enamide
Formula:  C32H29ClN8O5
Similarity:  0.8085106382978723
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-4-methylpent-2-enamide
Formula:  C29H32ClN7O3
Similarity:  0.7686567164179104
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-cyclopropylprop-2-enamide
Formula:  C29H30ClN7O3
Similarity:  0.762962962962963
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-2-cyano-N-(2-hydroxy-1,1-dimethyl-ethyl)-3-[3-(3,4,5-trimethoxyphenyl)-1H-indazol-5-yl]prop-2-enamide
Formula:  C29H30ClN7O3
Similarity:  0.762962962962963
Relative Targets:   Ribosomal protein S6 kinase alpha-3  |
Name:  (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-4,4-dimethylpent-2-enamide
Formula:  C30H34ClN7O3
Similarity:  0.7573529411764706
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-cyclopentylprop-2-enamide
Formula:  C31H34ClN7O3
Similarity:  0.7253521126760564
Relative Targets:   Epidermal growth factor receptor  |
Name:  (Z)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-3-(4-fluorophenyl)-2-(trifluoromethyl)prop-2-enamide
Formula:  C32H29ClF4N6O3
Similarity:  0.7162162162162162
Relative Targets:   Epidermal growth factor receptor  |
Name:  WZ4002
Formula:  C25H27ClN6O3
Similarity:  0.7099236641221374
Relative Targets:   Epidermal growth factor receptor  | Dipeptidyl peptidase 1  |
Name:  (Z)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-3-(4-methoxyphenyl)-2-(trifluoromethyl)prop-2-enamide
Formula:  C33H32ClF3N6O4
Similarity:  0.7019867549668874
Relative Targets:   Epidermal growth factor receptor  |
Name:  (Z)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-3-[4-(dimethylamino)phenyl]-2-(trifluoromethyl)prop-2-enamide
Formula:  C34H35ClF3N7O3
Similarity:  0.6928104575163399
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-3-cyclopropylprop-2-enamide
Formula:  C28H31ClN6O3
Similarity:  0.6642857142857143
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[3-chloro-6-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-2-pyridyl]oxy]phenyl]prop-2-enamide
Formula:  C26H28ClN5O3
Similarity:  0.6231884057971014
Relative Targets:   Dipeptidyl peptidase 1  |