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Approved Drugs
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Inhibitors
Name: (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(4-fluorophenyl)prop-2-enamide
Formula: C32H29ClFN7O3
Similarity: 0.8759124087591241
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(4-methylsulfanylphenyl)prop-2-enamide
Formula: C33H32ClN7O3S
Similarity: 0.8705035971223022
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(4-cyanophenyl)prop-2-enamide
Formula: C33H29ClN8O3
Similarity: 0.8571428571428571
Relative Targets: Epidermal growth factor receptor |
Name: (Z)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-3-[4-(dimethylamino)phenyl]-2-(trifluoromethyl)prop-2-enamide
Formula: C34H35ClF3N7O3
Similarity: 0.8472222222222222
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(4-nitrophenyl)prop-2-enamide
Formula: C32H29ClN8O5
Similarity: 0.8450704225352113
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-pyridin-4-ylprop-2-enamide
Formula: C31H29ClN8O3
Similarity: 0.8214285714285714
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(3-nitrophenyl)prop-2-enamide
Formula: C32H29ClN8O5
Similarity: 0.782312925170068
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(furan-2-yl)prop-2-enamide
Formula: C30H28ClN7O4
Similarity: 0.7746478873239436
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-4-methylpent-2-enamide
Formula: C29H32ClN7O3
Similarity: 0.7553956834532374
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(1H-imidazol-5-yl)prop-2-enamide
Formula: C29H28ClN9O3
Similarity: 0.75
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-4,4-dimethylpent-2-enamide
Formula: C30H34ClN7O3
Similarity: 0.7446808510638298
Relative Targets: Epidermal growth factor receptor |
Name: (Z)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-3-(4-fluorophenyl)-2-(trifluoromethyl)prop-2-enamide
Formula: C32H29ClF4N6O3
Similarity: 0.74
Relative Targets: Epidermal growth factor receptor |
Name: (Z)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-3-(4-methoxyphenyl)-2-(trifluoromethyl)prop-2-enamide
Formula: C33H32ClF3N6O4
Similarity: 0.7368421052631579
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-cyclopropylprop-2-enamide
Formula: C29H30ClN7O3
Similarity: 0.7253521126760564
Relative Targets: Epidermal growth factor receptor |
Name: (E)-2-cyano-N-(2-hydroxy-1,1-dimethyl-ethyl)-3-[3-(3,4,5-trimethoxyphenyl)-1H-indazol-5-yl]prop-2-enamide
Formula: C29H30ClN7O3
Similarity: 0.7253521126760564
Relative Targets: Ribosomal protein S6 kinase alpha-3 |
Name: (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-cyclopentylprop-2-enamide
Formula: C31H34ClN7O3
Similarity: 0.6912751677852349
Relative Targets: Epidermal growth factor receptor |
Name: WZ4002
Formula: C25H27ClN6O3
Similarity: 0.6739130434782609
Relative Targets: Epidermal growth factor receptor | Dipeptidyl peptidase 1 |
Name: (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-3-cyclopropylprop-2-enamide
Formula: C28H31ClN6O3
Similarity: 0.6326530612244898
Relative Targets: Epidermal growth factor receptor |
Name: N-[3-[[3-(dimethylamino)-6-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-2-pyridyl]oxy]phenyl]prop-2-enamide
Formula: C28H34N6O3
Similarity: 0.5945945945945946
Relative Targets: Dipeptidyl peptidase 1 |