CovalentInDB

Name: (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(3-nitrophenyl)prop-2-enamide

Formula: C₃₂H₂₉ClN₈O₅

Similarity: 0.8848920863309353

Relative Targets: Epidermal growth factor receptor |

Name: (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(4-fluorophenyl)prop-2-enamide

Formula: C₃₂H₂₉ClFN₇O₃

Similarity: 0.8759124087591241

Relative Targets: Epidermal growth factor receptor |

Name: (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(4-methylsulfanylphenyl)prop-2-enamide

Formula: C₃₃H₃₂ClN₇O₃S

Similarity: 0.8571428571428571

Relative Targets: Epidermal growth factor receptor |

Name: (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(4-cyanophenyl)prop-2-enamide

Formula: C₃₃H₂₉ClN₈O₃

Similarity: 0.8571428571428571

Relative Targets: Epidermal growth factor receptor |

Name: (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-[4-(dimethylamino)phenyl]prop-2-enamide

Formula: C₃₄H₃₅ClN₈O₃

Similarity: 0.8450704225352113

Relative Targets: Epidermal growth factor receptor |

Name: (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-pyridin-4-ylprop-2-enamide

Formula: C₃₁H₂₉ClN₈O₃

Similarity: 0.8214285714285714

Relative Targets: Epidermal growth factor receptor |

Name: (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(furan-2-yl)prop-2-enamide

Formula: C₃₀H₂₈ClN₇O₄

Similarity: 0.7746478873239436

Relative Targets: Epidermal growth factor receptor |

Name: (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(1H-imidazol-5-yl)prop-2-enamide

Formula: C₂₉H₂₈ClN₉O₃

Similarity: 0.75

Relative Targets: Epidermal growth factor receptor |

Name: (Z)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-3-(4-fluorophenyl)-2-(trifluoromethyl)prop-2-enamide

Formula: C₃₂H₂₉ClF₄N₆O₃

Similarity: 0.74

Relative Targets: Epidermal growth factor receptor |

Name: (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-4-methylpent-2-enamide

Formula: C₂₉H₃₂ClN₇O₃

Similarity: 0.7304964539007093

Relative Targets: Epidermal growth factor receptor |

Name: (Z)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-3-(4-methoxyphenyl)-2-(trifluoromethyl)prop-2-enamide

Formula: C₃₃H₃₂ClF₃N₆O₄

Similarity: 0.7254901960784313

Relative Targets: Epidermal growth factor receptor |

Name: (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-cyclopropylprop-2-enamide

Formula: C₂₉H₃₀ClN₇O₃

Similarity: 0.7253521126760564

Relative Targets: Epidermal growth factor receptor |

Name: (E)-2-cyano-N-(2-hydroxy-1,1-dimethyl-ethyl)-3-[3-(3,4,5-trimethoxyphenyl)-1H-indazol-5-yl]prop-2-enamide

Formula: C₂₉H₃₀ClN₇O₃

Similarity: 0.7253521126760564

Relative Targets: Ribosomal protein S6 kinase alpha-3 |

Name: (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-4,4-dimethylpent-2-enamide

Formula: C₃₀H₃₄ClN₇O₃

Similarity: 0.7202797202797203

Relative Targets: Epidermal growth factor receptor |

Name: (Z)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-3-[4-(dimethylamino)phenyl]-2-(trifluoromethyl)prop-2-enamide

Formula: C₃₄H₃₅ClF₃N₇O₃

Similarity: 0.7161290322580646

Relative Targets: Epidermal growth factor receptor |