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Approved Drugs
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Inhibitors
Name: (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(4-fluorophenyl)prop-2-enamide
Formula: C32H29ClFN7O3
Similarity: 0.8888888888888888
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-[4-(dimethylamino)phenyl]prop-2-enamide
Formula: C34H35ClN8O3
Similarity: 0.8705035971223022
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(4-cyanophenyl)prop-2-enamide
Formula: C33H29ClN8O3
Similarity: 0.8695652173913043
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(4-nitrophenyl)prop-2-enamide
Formula: C32H29ClN8O5
Similarity: 0.8571428571428571
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-pyridin-4-ylprop-2-enamide
Formula: C31H29ClN8O3
Similarity: 0.8333333333333334
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(3-nitrophenyl)prop-2-enamide
Formula: C32H29ClN8O5
Similarity: 0.7931034482758621
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(furan-2-yl)prop-2-enamide
Formula: C30H28ClN7O4
Similarity: 0.7857142857142857
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(1H-imidazol-5-yl)prop-2-enamide
Formula: C29H28ClN9O3
Similarity: 0.7605633802816901
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-4-methylpent-2-enamide
Formula: C29H32ClN7O3
Similarity: 0.7536231884057971
Relative Targets: Epidermal growth factor receptor |
Name: (Z)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-3-(4-fluorophenyl)-2-(trifluoromethyl)prop-2-enamide
Formula: C32H29ClF4N6O3
Similarity: 0.75
Relative Targets: Epidermal growth factor receptor |
Name: (Z)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-3-(4-methoxyphenyl)-2-(trifluoromethyl)prop-2-enamide
Formula: C33H32ClF3N6O4
Similarity: 0.7466666666666667
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-4,4-dimethylpent-2-enamide
Formula: C30H34ClN7O3
Similarity: 0.7428571428571429
Relative Targets: Epidermal growth factor receptor |
Name: (Z)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-3-[4-(dimethylamino)phenyl]-2-(trifluoromethyl)prop-2-enamide
Formula: C34H35ClF3N7O3
Similarity: 0.7368421052631579
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-cyclopropylprop-2-enamide
Formula: C29H30ClN7O3
Similarity: 0.7357142857142858
Relative Targets: Epidermal growth factor receptor |
Name: (E)-2-cyano-N-(2-hydroxy-1,1-dimethyl-ethyl)-3-[3-(3,4,5-trimethoxyphenyl)-1H-indazol-5-yl]prop-2-enamide
Formula: C29H30ClN7O3
Similarity: 0.7357142857142858
Relative Targets: Ribosomal protein S6 kinase alpha-3 |
Name: (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-cyclopentylprop-2-enamide
Formula: C31H34ClN7O3
Similarity: 0.7006802721088435
Relative Targets: Epidermal growth factor receptor |
Name: WZ4002
Formula: C25H27ClN6O3
Similarity: 0.6838235294117647
Relative Targets: Epidermal growth factor receptor | Dipeptidyl peptidase 1 |
Name: (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-3-cyclopropylprop-2-enamide
Formula: C28H31ClN6O3
Similarity: 0.6413793103448275
Relative Targets: Epidermal growth factor receptor |
Name: N-[3-[[3-chloro-6-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-2-pyridyl]oxy]phenyl]prop-2-enamide
Formula: C26H28ClN5O3
Similarity: 0.6013986013986014
Relative Targets: Dipeptidyl peptidase 1 |