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Approved Drugs
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Inhibitors
Name: (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(4-methylsulfanylphenyl)prop-2-enamide
Formula: C33H32ClN7O3S
Similarity: 0.8888888888888888
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(4-cyanophenyl)prop-2-enamide
Formula: C33H29ClN8O3
Similarity: 0.8888888888888888
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(4-nitrophenyl)prop-2-enamide
Formula: C32H29ClN8O5
Similarity: 0.8759124087591241
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-[4-(dimethylamino)phenyl]prop-2-enamide
Formula: C34H35ClN8O3
Similarity: 0.8759124087591241
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-pyridin-4-ylprop-2-enamide
Formula: C31H29ClN8O3
Similarity: 0.8518518518518519
Relative Targets: Epidermal growth factor receptor |
Name: (Z)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-3-(4-fluorophenyl)-2-(trifluoromethyl)prop-2-enamide
Formula: C32H29ClF4N6O3
Similarity: 0.841726618705036
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(3-nitrophenyl)prop-2-enamide
Formula: C32H29ClN8O5
Similarity: 0.8098591549295775
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(furan-2-yl)prop-2-enamide
Formula: C30H28ClN7O4
Similarity: 0.8029197080291971
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(1H-imidazol-5-yl)prop-2-enamide
Formula: C29H28ClN9O3
Similarity: 0.7769784172661871
Relative Targets: Epidermal growth factor receptor |
Name: (Z)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-3-(4-methoxyphenyl)-2-(trifluoromethyl)prop-2-enamide
Formula: C33H32ClF3N6O4
Similarity: 0.7619047619047619
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-4-methylpent-2-enamide
Formula: C29H32ClN7O3
Similarity: 0.7573529411764706
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-cyclopropylprop-2-enamide
Formula: C29H30ClN7O3
Similarity: 0.7518248175182481
Relative Targets: Epidermal growth factor receptor |
Name: (E)-2-cyano-N-(2-hydroxy-1,1-dimethyl-ethyl)-3-[3-(3,4,5-trimethoxyphenyl)-1H-indazol-5-yl]prop-2-enamide
Formula: C29H30ClN7O3
Similarity: 0.7518248175182481
Relative Targets: Ribosomal protein S6 kinase alpha-3 |
Name: (Z)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-3-[4-(dimethylamino)phenyl]-2-(trifluoromethyl)prop-2-enamide
Formula: C34H35ClF3N7O3
Similarity: 0.7516778523489933
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-4,4-dimethylpent-2-enamide
Formula: C30H34ClN7O3
Similarity: 0.7463768115942029
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-cyclopentylprop-2-enamide
Formula: C31H34ClN7O3
Similarity: 0.7152777777777778
Relative Targets: Epidermal growth factor receptor |
Name: WZ4002
Formula: C25H27ClN6O3
Similarity: 0.6992481203007519
Relative Targets: Epidermal growth factor receptor | Dipeptidyl peptidase 1 |
Name: (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-3-cyclopropylprop-2-enamide
Formula: C28H31ClN6O3
Similarity: 0.6549295774647887
Relative Targets: Epidermal growth factor receptor |
Name: N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxy-5-fluoro-phenyl]prop-2-enamide
Formula: C25H26ClFN6O3
Similarity: 0.6285714285714286
Relative Targets: Epidermal growth factor receptor |