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Approved Drugs
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Inhibitors
Name: (Z)-N-[4-(3-Bromoanilino)-7-methoxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide
Formula: C21H21BrFN5O2
Similarity: 1.0
Relative Targets: Epidermal growth factor receptor |
Name: (Z)-N-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide
Formula: C21H20ClF2N5O2
Similarity: 0.7708333333333334
Relative Targets: Tyrosine-protein kinase JAK2 | Epidermal growth factor receptor | Hepatocyte growth factor receptor | Platelet-derived growth factor receptor alpha | Fibroblast growth factor receptor 2 | RAC-beta serine/threonine-protein kinase | Potassium voltage-gated channel subfamily H member 2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (Z)-N-[4-[3-Chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-methoxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide
Formula: C28H26ClF2N5O3
Similarity: 0.6581196581196581
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-[3-Chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-methoxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide
Formula: C28H26ClF2N5O3
Similarity: 0.6581196581196581
Relative Targets: Epidermal growth factor receptor |
Name: N-[4-(3-bromoanilino)-7-[4-(dimethylamino)butoxy]quinazolin-6-yl]prop-2-enamide
Formula: C23H26BrN5O2
Similarity: 0.6226415094339622
Relative Targets: Epidermal growth factor receptor |
Name: (Z)-N-[4-[3-Chloro-4-(cyclopropylmethoxy)anilino]-7-ethoxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide
Formula: C26H29ClFN5O3
Similarity: 0.6086956521739131
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-[3-Chloro-4-(cyclopropylmethoxy)anilino]-7-ethoxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide
Formula: C26H29ClFN5O3
Similarity: 0.6086956521739131
Relative Targets: Epidermal growth factor receptor |
Name: (Z)-N-[4-(3-Chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide
Formula: C24H24ClF2N5O3
Similarity: 0.6052631578947368
Relative Targets: Epidermal growth factor receptor | Potassium voltage-gated channel subfamily H member 2 |
Name: (E)-N-[4-(3-Chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide
Formula: C24H24ClF2N5O3
Similarity: 0.6052631578947368
Relative Targets: Epidermal growth factor receptor | Potassium voltage-gated channel subfamily H member 2 |
Name: (Z)-N-[4-[3-Chloro-4-(pyridin-2-ylmethoxy)anilino]-7-ethoxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide
Formula: C28H28ClFN6O3
Similarity: 0.5853658536585366
Relative Targets: Epidermal growth factor receptor | Potassium voltage-gated channel subfamily H member 2 |
Name: (E)-N-[4-[3-Chloro-4-(pyridin-2-ylmethoxy)anilino]-7-ethoxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide
Formula: C28H28ClFN6O3
Similarity: 0.5853658536585366
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-bromoanilino)-3-cyano-7-methoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C23H22BrN5O2
Similarity: 0.5833333333333334
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula: C20H20BrN5O
Similarity: 0.5784313725490197
Relative Targets: Proto-oncogene tyrosine-protein kinase Src | Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (Z)-N-[4-[3-Chloro-4-(6-methylpyridin-3-yl)oxyanilino]-7-ethoxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide
Formula: C28H28ClFN6O3
Similarity: 0.5772357723577236
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-[3-Chloro-4-(6-methylpyridin-3-yl)oxyanilino]-7-ethoxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide
Formula: C28H28ClFN6O3
Similarity: 0.5772357723577236
Relative Targets: Epidermal growth factor receptor |
Name: (E)-4-[cyclopropyl(methyl)amino]-N-[4-(3-ethynylanilino)-7-methoxy-quinazolin-6-yl]but-2-enamide
Formula: C25H25N5O2
Similarity: 0.5625
Relative Targets: Epidermal growth factor receptor |
Name: (E)-4-(dimethylamino)-N-[4-(3-ethynylanilino)-7-(2-methoxyethoxy)quinazolin-6-yl]but-2-enamide
Formula: C25H27N5O3
Similarity: 0.5614035087719298
Relative Targets: Epidermal growth factor receptor |
Name: (Z)-N-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-2-fluoro-4-piperidin-1-ylbut-2-enamide
Formula: C24H24ClF2N5O2
Similarity: 0.5470085470085471
Relative Targets: Epidermal growth factor receptor | Potassium voltage-gated channel subfamily H member 2 |
Name: (Z)-N-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-2-fluoro-4-morpholin-4-ylbut-2-enamide
Formula: C23H22ClF2N5O3
Similarity: 0.5470085470085471
Relative Targets: Epidermal growth factor receptor |