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Name:  Dacomitinib

Formula:  C₂₄H₂₅ClFN₅O₂

Similarity:  0.6532258064516129

Name:  Afatinib

Formula:  C₂₄H₂₅ClFN₅O₃

Similarity:  0.6299212598425197

Name:  (E)-N-[4-(3-Chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-2-fluoro-4-piperidin-1-ylbut-2-enamide

Formula:  C₂₇H₂₈ClF₂N₅O₃

Similarity:  1.0

Relative Targets:   Epidermal growth factor receptor  |

Name:  (Z)-N-[4-(3-Chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-2-fluoro-4-morpholin-4-ylbut-2-enamide

Formula:  C₂₆H₂₆ClF₂N₅O₄

Similarity:  0.8487394957983193

Relative Targets:   Epidermal growth factor receptor  | Potassium voltage-gated channel subfamily H member 2  |

Name:  (E)-N-[4-(3-Chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-2-fluoro-4-morpholin-4-ylbut-2-enamide

Formula:  C₂₆H₂₆ClF₂N₅O₄

Similarity:  0.8487394957983193

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(1-piperidyl)but-2-enamide

Formula:  C₂₇H₂₉ClFN₅O₃

Similarity:  0.8319327731092437

Relative Targets:   Epidermal growth factor receptor  |

Name:  (Z)-N-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-2-fluoro-4-piperidin-1-ylbut-2-enamide

Formula:  C₂₄H₂₄ClF₂N₅O₂

Similarity:  0.8

Relative Targets:   Epidermal growth factor receptor  | Potassium voltage-gated channel subfamily H member 2  |

Name:  (E)-N-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-2-fluoro-4-piperidin-1-ylbut-2-enamide

Formula:  C₂₄H₂₄ClF₂N₅O₂

Similarity:  0.8

Relative Targets:   Epidermal growth factor receptor  |

Name:  (Z)-N-[4-(3-Chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide

Formula:  C₂₄H₂₄ClF₂N₅O₃

Similarity:  0.7416666666666667

Relative Targets:   Epidermal growth factor receptor  | Potassium voltage-gated channel subfamily H member 2  |

Name:  (E)-N-[4-(3-Chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide

Formula:  C₂₄H₂₄ClF₂N₅O₃

Similarity:  0.7416666666666667

Relative Targets:   Epidermal growth factor receptor  | Potassium voltage-gated channel subfamily H member 2  |

Name:  (Z)-N-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-2-fluoro-4-morpholin-4-ylbut-2-enamide

Formula:  C₂₃H₂₂ClF₂N₅O₃

Similarity:  0.7107438016528925

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-2-fluoro-4-morpholin-4-ylbut-2-enamide

Formula:  C₂₃H₂₂ClF₂N₅O₃

Similarity:  0.7107438016528925

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(4-oxo-1-piperidyl)but-2-enamide

Formula:  C₂₇H₂₇ClFN₅O₄

Similarity:  0.6923076923076923

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(1-oxidothiomorpholin-1-ium-4-yl)but-2-enamide

Formula:  C₂₆H₂₇ClFN₅O₄S

Similarity:  0.6923076923076923

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide

Formula:  C₂₁H₁₈ClFN₄O₃

Similarity:  0.6752136752136753

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(3,3-difluoroazetidin-1-yl)but-2-enamide

Formula:  C₂₅H₂₃ClF₃N₅O₃

Similarity:  0.6666666666666666

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-ethynylanilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(1-piperidyl)but-2-enamide

Formula:  C₂₉H₃₁N₅O₃

Similarity:  0.6590909090909091

Relative Targets:   Epidermal growth factor receptor  |

Name:  Dacomitinib

Formula:  C₂₄H₂₅ClFN₅O₂

Similarity:  0.6532258064516129

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Receptor tyrosine-protein kinase erbB-4  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(cyclopropylamino)but-2-enamide

Formula:  C₂₅H₂₅ClFN₅O₃

Similarity:  0.6356589147286822

Relative Targets:   Epidermal growth factor receptor  |

Name:  Afatinib

Formula:  C₂₄H₂₅ClFN₅O₃

Similarity:  0.6299212598425197

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Dipeptidyl peptidase 1  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(dicyclopropylamino)but-2-enamide

Formula:  C₂₈H₂₉ClFN₅O₃

Similarity:  0.6222222222222222

Relative Targets:   Epidermal growth factor receptor  |