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Approved Drugs
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Inhibitors
Name:  N-[3-[[[5-Chloro-2-[[1-(2-hydroxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]amino]methyl]phenyl]prop-2-enamide
Formula:  C19H20ClN7O2
Similarity:  0.797752808988764
Relative Targets:   Tyrosine-protein kinase JAK1  | Non-receptor tyrosine-protein kinase TYK2  | Dual specificity protein kinase TTK  | Tyrosine-protein kinase JAK3  |
Name:  N-[3-[[[5-Chloro-2-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]amino]methyl]phenyl]prop-2-enamide
Formula:  C20H22ClN7O2
Similarity:  0.7912087912087912
Relative Targets:   Aurora kinase A  | Tyrosine-protein kinase JAK1  | Non-receptor tyrosine-protein kinase TYK2  | Dual specificity protein kinase TTK  | Receptor-type tyrosine-protein kinase FLT3  | Tyrosine-protein kinase JAK3  |
Name:  N-[3-[[2-[(1-methylpyrazol-4-yl)amino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide
Formula:  C21H19N7O2
Similarity:  0.63
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  N-[2-[5-Chloro-2-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C17H15ClN6O2
Similarity:  0.6063829787234043
Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  | Dual specificity mitogen-activated protein kinase kinase 1  |
Name:  N-[3-[[[5-Chloro-2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]amino]methyl]phenyl]prop-2-enamide
Formula:  C24H25ClN6O2
Similarity:  0.6018518518518519
Relative Targets:   Tyrosine-protein kinase JAK1  | Dual specificity protein kinase TTK  | Tyrosine-protein kinase JAK3  |
Name:  N-[3-[[[5-Chloro-2-(3,5-difluoro-4-morpholin-4-ylanilino)pyrimidin-4-yl]amino]methyl]phenyl]prop-2-enamide
Formula:  C24H23ClF2N6O2
Similarity:  0.5803571428571429
Relative Targets:   Tyrosine-protein kinase JAK1  | Dual specificity protein kinase TTK  | Tyrosine-protein kinase JAK3  |
Name:  Jak3-IN-1
Formula:  C26H30ClN7O2
Similarity:  0.5652173913043478
Relative Targets:   Serine/threonine-protein kinase Sgk1  | Epidermal growth factor receptor  | Platelet-derived growth factor receptor beta  | Tyrosine-protein kinase JAK1  | Non-receptor tyrosine-protein kinase TYK2  | Dual specificity protein kinase TTK  | Receptor-type tyrosine-protein kinase FLT3  | Tyrosine-protein kinase Blk  | Tyrosine-protein kinase JAK3  | Focal adhesion kinase 1  | Tyrosine-protein kinase BTK  | Tyrosine-protein kinase ITK/TSK  | Receptor tyrosine-protein kinase erbB-4  |
Name:  N-[3-[6-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]phenyl]prop-2-enamide
Formula:  C17H16N6O
Similarity:  0.5531914893617021
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  N-[3-[[2-[(1-Methylpyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide
Formula:  C19H17N7O2
Similarity:  0.5339805825242718
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[2-[[5-Chloro-2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide
Formula:  C17H16ClN7O
Similarity:  0.51
Relative Targets:   Mitogen-activated protein kinase 1  |
Name:  N-[3-[[2-[[1-(2-hydroxyethyl)pyrazol-4-yl]amino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide
Formula:  C22H21N7O3
Similarity:  0.5089285714285714
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  N-[3-[[2-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide
Formula:  C23H23N7O3
Similarity:  0.5087719298245614
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  N-[3-[2-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]phenyl]prop-2-enamide
Formula:  C19H20N6O2
Similarity:  0.5048543689320388
Relative Targets:   Tyrosine-protein kinase JAK3  |