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Approved Drugs
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Inhibitors
Name: (E)-N-[4-[3-Chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-methoxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide
Formula: C28H26ClF2N5O3
Similarity: 1.0
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula: C30H31ClFN5O4
Similarity: 0.732824427480916
Relative Targets: Epidermal growth factor receptor |
Name: (Z)-N-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide
Formula: C21H20ClF2N5O2
Similarity: 0.7192982456140351
Relative Targets: Tyrosine-protein kinase JAK2 | Epidermal growth factor receptor | Hepatocyte growth factor receptor | Platelet-derived growth factor receptor alpha | Fibroblast growth factor receptor 2 | RAC-beta serine/threonine-protein kinase | Potassium voltage-gated channel subfamily H member 2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (Z)-N-[4-[3-Chloro-4-(pyridin-2-ylmethoxy)anilino]-7-ethoxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide
Formula: C28H28ClFN6O3
Similarity: 0.7131782945736435
Relative Targets: Epidermal growth factor receptor | Potassium voltage-gated channel subfamily H member 2 |
Name: (E)-N-[4-[3-Chloro-4-(pyridin-2-ylmethoxy)anilino]-7-ethoxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide
Formula: C28H28ClFN6O3
Similarity: 0.7131782945736435
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-(2-ethoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula: C31H33ClFN5O4
Similarity: 0.7037037037037037
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-(2-methoxyethoxy)quinazolin-6-yl]prop-2-enamide
Formula: C27H24ClFN4O4
Similarity: 0.6875
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula: C31H31ClFN5O4
Similarity: 0.6861313868613139
Relative Targets: Epidermal growth factor receptor |
Name: (Z)-N-[4-[3-Chloro-4-(6-methylpyridin-3-yl)oxyanilino]-7-ethoxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide
Formula: C28H28ClFN6O3
Similarity: 0.6793893129770993
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-[3-Chloro-4-(6-methylpyridin-3-yl)oxyanilino]-7-ethoxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide
Formula: C28H28ClFN6O3
Similarity: 0.6793893129770993
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]pyrido[3,4-d]pyrimidin-6-yl]-4-(dimethylamino)but-2-enamide
Formula: C26H24ClFN6O2
Similarity: 0.6640625
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (Z)-N-[4-(3-Bromoanilino)-7-methoxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide
Formula: C21H21BrFN5O2
Similarity: 0.6581196581196581
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-Bromoanilino)-7-methoxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide
Formula: C21H21BrFN5O2
Similarity: 0.6581196581196581
Relative Targets: Epidermal growth factor receptor |
Name: (Z)-N-[4-[3-Chloro-4-(cyclopropylmethoxy)anilino]-7-ethoxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide
Formula: C26H29ClFN5O3
Similarity: 0.6484375
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-[3-Chloro-4-(cyclopropylmethoxy)anilino]-7-ethoxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide
Formula: C26H29ClFN5O3
Similarity: 0.6484375
Relative Targets: Epidermal growth factor receptor |
Name: N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide
Formula: C28H24ClFN4O4
Similarity: 0.6296296296296297
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-ethoxy-quinazolin-6-yl]-4-pyrrolidin-1-yl-but-2-enamide
Formula: C31H31ClFN5O3
Similarity: 0.6126760563380281
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide
Formula: C31H29ClFN5O3
Similarity: 0.6028368794326241
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 |
Name: (E)-N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-ethoxy-quinazolin-6-yl]-4-(4-methylpiperazin-1-yl)but-2-enamide
Formula: C32H34ClFN6O3
Similarity: 0.6027397260273972
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |