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Approved Drugs

Name:  Olmutinib

Formula:  C26H26N6O2S

Similarity:  0.7894736842105263

Inhibitors

Name:  N-[4-[[2-[4-(4-Methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide

Formula:  C26H27N7O2

Similarity:  0.8545454545454545

Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  |

Name:  N-[3-[[2-[4-(4-methylpiperazin-1-yl)anilino]-9H-purin-6-yl]oxy]phenyl]prop-2-enamide

Formula:  C25H26N8O2

Similarity:  0.8214285714285714

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[3-fluoro-4-(4-methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide

Formula:  C26H26FN7O2

Similarity:  0.8070175438596491

Relative Targets:   Epidermal growth factor receptor  | Tyrosine-protein kinase ITK/TSK  |

Name:  N-[3-[[2-[3-amino-4-(4-methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide

Formula:  C26H28N8O2

Similarity:  0.8070175438596491

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[3-chloro-4-(4-methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide

Formula:  C26H26ClN7O2

Similarity:  0.8070175438596491

Relative Targets:   Epidermal growth factor receptor  |

Name:  Olmutinib

Formula:  C26H26N6O2S

Similarity:  0.7894736842105263

Relative Targets:   Tyrosine-protein kinase BTK  |

Name:  N-[3-[[2-[3-methoxy-4-(4-methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide

Formula:  C27H29N7O3

Similarity:  0.7863247863247863

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[4-(4-methylpiperazin-1-yl)-3-nitro-anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide

Formula:  C26H26N8O4

Similarity:  0.773109243697479

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C24H25ClN6O2

Similarity:  0.7589285714285714

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-bromo-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C24H25BrN6O2

Similarity:  0.7589285714285714

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C24H26N6O2

Similarity:  0.7410714285714286

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[3-chloro-6-[4-(4-methylpiperazin-1-yl)anilino]-2-pyridyl]oxy]phenyl]prop-2-enamide

Formula:  C25H26ClN5O2

Similarity:  0.7280701754385965

Relative Targets:   Dipeptidyl peptidase 1  |

Name:  N-[3-[2-[4-(4-methylpiperazin-1-yl)anilino]-5-(trifluoromethyl)pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C25H25F3N6O2

Similarity:  0.7142857142857143

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[(1-Methylpyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide

Formula:  C19H17N7O2

Similarity:  0.6339285714285714

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]sulfanylphenyl]prop-2-enamide

Formula:  C24H25ClN6OS

Similarity:  0.628099173553719

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-[4-[(4-methylpiperazin-1-yl)methyl]anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C25H27ClN6O2

Similarity:  0.6260162601626016

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[(1-Methylpyrazol-3-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide

Formula:  C19H17N7O2

Similarity:  0.6194690265486725

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[2-[6-Amino-5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C24H26ClN7O2

Similarity:  0.6178861788617886

Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  | Dual specificity mitogen-activated protein kinase kinase 1  |

Name:  N-[3-[5-chloro-2-[4-(4-methylpiperazine-1-carbonyl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C25H25ClN6O3

Similarity:  0.616

Relative Targets:   Epidermal growth factor receptor  |