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Approved Drugs
Inhibitors
Name:  N-[3-[[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide
Formula:  C29H31N7O3
Similarity:  0.8416666666666667
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  N-[3-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide
Formula:  C27H28N8O3
Similarity:  0.8319327731092437
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[2-[2-Methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxopyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide
Formula:  C29H31N7O3
Similarity:  0.8181818181818182
Relative Targets:   Epidermal growth factor receptor  | Tyrosine-protein kinase JAK3  |
Name:  N-[3-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-6,7-dioxo-5H-pteridin-8-yl]phenyl]prop-2-enamide
Formula:  C27H28N8O4
Similarity:  0.7741935483870968
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[2-[2-ethoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide
Formula:  C30H33N7O3
Similarity:  0.7637795275590551
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  N-[3-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-6,7-dioxo-pteridin-8-yl]phenyl]prop-2-enamide
Formula:  C28H30N8O4
Similarity:  0.7619047619047619
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[2-[2-isopropoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide
Formula:  C31H35N7O3
Similarity:  0.751937984496124
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  N-[3-[5-ethyl-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-6,7-dioxo-pteridin-8-yl]phenyl]prop-2-enamide
Formula:  C29H32N8O4
Similarity:  0.7441860465116279
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide
Formula:  C27H28N8O3
Similarity:  0.744
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[2-[4-(4-acetylpiperazin-1-yl)-2-methoxy-anilino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide
Formula:  C30H31N7O4
Similarity:  0.7384615384615385
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  N-[3-[5-isopropyl-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-6,7-dioxo-pteridin-8-yl]phenyl]prop-2-enamide
Formula:  C30H34N8O4
Similarity:  0.732824427480916
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-6,7-dioxo-5-propyl-pteridin-8-yl]phenyl]prop-2-enamide
Formula:  C30H34N8O4
Similarity:  0.7272727272727273
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide
Formula:  C28H32N8O3
Similarity:  0.71875
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide
Formula:  C30H33N7O3
Similarity:  0.7153846153846154
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  N-[3-[[5-ethyl-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide
Formula:  C31H35N7O3
Similarity:  0.6992481203007519
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  N-[3-[3-isopropyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide
Formula:  C30H36N8O3
Similarity:  0.6917293233082706
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[2-[4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide
Formula:  C26H26N8O2
Similarity:  0.6904761904761905
Relative Targets:   Epidermal growth factor receptor  | Tyrosine-protein kinase BTK  |
Name:  N-[3-[3-cyclopropyl-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide
Formula:  C30H34N8O3
Similarity:  0.6865671641791045
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-2-oxo-3-phenyl-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide
Formula:  C33H34N8O3
Similarity:  0.6857142857142857
Relative Targets:   Epidermal growth factor receptor  |