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Approved Drugs

Name:  Neratinib

Formula:  C30H29ClN6O3

Similarity:  0.6666666666666666

Inhibitors

Name:  (E)-N-[4-[3-Chloro-4-(pyridin-2-ylmethoxy)anilino]-7-ethoxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide

Formula:  C28H28ClFN6O3

Similarity:  1.0

Relative Targets:   Epidermal growth factor receptor  |

Name:  (Z)-N-[4-[3-Chloro-4-(6-methylpyridin-3-yl)oxyanilino]-7-ethoxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide

Formula:  C28H28ClFN6O3

Similarity:  0.7401574803149606

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-[3-Chloro-4-(6-methylpyridin-3-yl)oxyanilino]-7-ethoxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide

Formula:  C28H28ClFN6O3

Similarity:  0.7401574803149606

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C29H31ClN6O4

Similarity:  0.7384615384615385

Relative Targets:   Epidermal growth factor receptor  |

Name:  (Z)-N-[4-[3-Chloro-4-(cyclopropylmethoxy)anilino]-7-ethoxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide

Formula:  C26H29ClFN5O3

Similarity:  0.7377049180327869

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-[3-Chloro-4-(cyclopropylmethoxy)anilino]-7-ethoxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide

Formula:  C26H29ClFN5O3

Similarity:  0.7377049180327869

Relative Targets:   Epidermal growth factor receptor  |

Name:  (Z)-N-[4-[3-Chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-methoxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide

Formula:  C28H26ClF2N5O3

Similarity:  0.7131782945736435

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-[3-Chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-methoxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide

Formula:  C28H26ClF2N5O3

Similarity:  0.7131782945736435

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide

Formula:  C30H29ClN6O3

Similarity:  0.6666666666666666

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-N-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C30H31ClN6O4

Similarity:  0.6666666666666666

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide

Formula:  C27H24ClN5O4

Similarity:  0.6102941176470589

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-(2-ethoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C31H33ClFN5O4

Similarity:  0.6041666666666666

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |

Name:  (E)-4-(dimethylamino)-N-[7-(2-methoxyethoxy)-4-[4-(2-pyridylmethoxy)anilino]quinazolin-6-yl]but-2-enamide

Formula:  C29H32N6O4

Similarity:  0.6

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C30H31ClFN5O4

Similarity:  0.5944055944055944

Relative Targets:   Epidermal growth factor receptor  |

Name:  (Z)-N-[4-(3-Bromoanilino)-7-methoxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide

Formula:  C21H21BrFN5O2

Similarity:  0.5853658536585366

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-Bromoanilino)-7-methoxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide

Formula:  C21H21BrFN5O2

Similarity:  0.5853658536585366

Relative Targets:   Epidermal growth factor receptor  |

Name:  (Z)-N-[4-[3-Chloro-4-(6-methylpyridin-3-yl)oxyanilino]-7-ethoxyquinazolin-6-yl]-2-fluoro-4-piperidin-1-ylbut-2-enamide

Formula:  C31H32ClFN6O3

Similarity:  0.5782312925170068

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-[3-Chloro-4-(6-methylpyridin-3-yl)oxyanilino]-7-ethoxyquinazolin-6-yl]-2-fluoro-4-piperidin-1-ylbut-2-enamide

Formula:  C31H32ClFN6O3

Similarity:  0.5782312925170068

Relative Targets:   Epidermal growth factor receptor  |