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Name:  Afatinib

Formula:  C₂₄H₂₅ClFN₅O₃

Similarity:  0.8148148148148148

Name:  Dacomitinib

Formula:  C₂₄H₂₅ClFN₅O₂

Similarity:  0.515625

Name:  (E)-N-[4-(3-Chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide

Formula:  C₂₄H₂₄ClF₂N₅O₃

Similarity:  1.0

Relative Targets:   Epidermal growth factor receptor  | Potassium voltage-gated channel subfamily H member 2  |

Name:  Afatinib

Formula:  C₂₄H₂₅ClFN₅O₃

Similarity:  0.8148148148148148

Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Dipeptidyl peptidase 1  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-6-[(3R)-tetrahydrofuran-3-yl]oxy-quinazolin-7-yl]-4-(dimethylamino)but-2-enamide

Formula:  C₂₄H₂₅ClFN₅O₃

Similarity:  0.7818181818181819

Relative Targets:   Epidermal growth factor receptor  |

Name:  (Z)-N-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide

Formula:  C₂₁H₂₀ClF₂N₅O₂

Similarity:  0.7788461538461539

Relative Targets:   Tyrosine-protein kinase JAK2  | Epidermal growth factor receptor  | Hepatocyte growth factor receptor  | Platelet-derived growth factor receptor alpha  | Fibroblast growth factor receptor 2  | RAC-beta serine/threonine-protein kinase  | Potassium voltage-gated channel subfamily H member 2  | Receptor tyrosine-protein kinase erbB-4  |

Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide

Formula:  C₂₁H₁₈ClFN₄O₃

Similarity:  0.7452830188679245

Relative Targets:   Epidermal growth factor receptor  |

Name:  (Z)-N-[4-(3-Chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-2-fluoro-4-morpholin-4-ylbut-2-enamide

Formula:  C₂₆H₂₆ClF₂N₅O₄

Similarity:  0.7416666666666667

Relative Targets:   Epidermal growth factor receptor  | Potassium voltage-gated channel subfamily H member 2  |

Name:  (E)-N-[4-(3-Chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-2-fluoro-4-morpholin-4-ylbut-2-enamide

Formula:  C₂₆H₂₆ClF₂N₅O₄

Similarity:  0.7416666666666667

Relative Targets:   Epidermal growth factor receptor  |

Name:  (Z)-N-[4-(3-Chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-2-fluoro-4-piperidin-1-ylbut-2-enamide

Formula:  C₂₇H₂₈ClF₂N₅O₃

Similarity:  0.7416666666666667

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-Chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-2-fluoro-4-piperidin-1-ylbut-2-enamide

Formula:  C₂₇H₂₈ClF₂N₅O₃

Similarity:  0.7416666666666667

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-cyano-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C₂₅H₂₅FN₆O₃

Similarity:  0.7008547008547008

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(isopropylamino)but-2-enamide

Formula:  C₂₅H₂₇ClFN₅O₃

Similarity:  0.7008547008547008

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-[4-chloro-3-(trifluoromethyl)anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(dimethylamino)but-2-enamide

Formula:  C₂₅H₂₅ClF₃N₅O₃

Similarity:  0.6916666666666667

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(cyclopropylamino)but-2-enamide

Formula:  C₂₅H₂₅ClFN₅O₃

Similarity:  0.6666666666666666

Relative Targets:   Epidermal growth factor receptor  |

Name:  (Z)-N-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-2-fluoro-4-morpholin-4-ylbut-2-enamide

Formula:  C₂₃H₂₂ClF₂N₅O₃

Similarity:  0.6610169491525424

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-2-fluoro-4-morpholin-4-ylbut-2-enamide

Formula:  C₂₃H₂₂ClF₂N₅O₃

Similarity:  0.6610169491525424

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(3,3-difluoroazetidin-1-yl)but-2-enamide

Formula:  C₂₅H₂₃ClF₃N₅O₃

Similarity:  0.6585365853658537

Relative Targets:   Epidermal growth factor receptor  |

Name:  (Z)-N-[4-[3-Chloro-4-(cyclopropylmethoxy)anilino]-7-ethoxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide

Formula:  C₂₆H₂₉ClFN₅O₃

Similarity:  0.6528925619834711

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-[3-Chloro-4-(cyclopropylmethoxy)anilino]-7-ethoxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide

Formula:  C₂₆H₂₉ClFN₅O₃

Similarity:  0.6528925619834711

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(dicyclopropylamino)but-2-enamide

Formula:  C₂₈H₂₉ClFN₅O₃

Similarity:  0.6507936507936508

Relative Targets:   Epidermal growth factor receptor  |