Searching results
Approved Drugs
Name: Dacomitinib
Formula: C24H25ClFN5O2
Similarity: 0.8113207547169812
Name: Afatinib
Formula: C24H25ClFN5O3
Similarity: 0.515625
Inhibitors
Name: (Z)-N-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-2-fluoro-4-piperidin-1-ylbut-2-enamide
Formula: C24H24ClF2N5O2
Similarity: 1.0
Relative Targets: Epidermal growth factor receptor | Potassium voltage-gated channel subfamily H member 2 |
Name: (Z)-N-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-2-fluoro-4-morpholin-4-ylbut-2-enamide
Formula: C23H22ClF2N5O3
Similarity: 0.8301886792452831
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-2-fluoro-4-morpholin-4-ylbut-2-enamide
Formula: C23H22ClF2N5O3
Similarity: 0.8301886792452831
Relative Targets: Epidermal growth factor receptor |
Name: Dacomitinib
Formula: C24H25ClFN5O2
Similarity: 0.8113207547169812
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (Z)-N-[4-(3-Chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-2-fluoro-4-piperidin-1-ylbut-2-enamide
Formula: C27H28ClF2N5O3
Similarity: 0.8
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-Chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-2-fluoro-4-piperidin-1-ylbut-2-enamide
Formula: C27H28ClF2N5O3
Similarity: 0.8
Relative Targets: Epidermal growth factor receptor |
Name: (Z)-N-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide
Formula: C21H20ClF2N5O2
Similarity: 0.7102803738317757
Relative Targets: Tyrosine-protein kinase JAK2 | Epidermal growth factor receptor | Hepatocyte growth factor receptor | Platelet-derived growth factor receptor alpha | Fibroblast growth factor receptor 2 | RAC-beta serine/threonine-protein kinase | Potassium voltage-gated channel subfamily H member 2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(1-piperidyl)but-2-enamide
Formula: C26H29ClFN5O3
Similarity: 0.7033898305084746
Relative Targets: Epidermal growth factor receptor |
Name: (Z)-N-[4-(3-Chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-2-fluoro-4-morpholin-4-ylbut-2-enamide
Formula: C26H26ClF2N5O4
Similarity: 0.6829268292682927
Relative Targets: Epidermal growth factor receptor | Potassium voltage-gated channel subfamily H member 2 |
Name: (E)-N-[4-(3-Chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-2-fluoro-4-morpholin-4-ylbut-2-enamide
Formula: C26H26ClF2N5O4
Similarity: 0.6829268292682927
Relative Targets: Epidermal growth factor receptor |
Name: (Z)-N-[4-[3-Chloro-4-(6-methylpyridin-3-yl)oxyanilino]-7-ethoxyquinazolin-6-yl]-2-fluoro-4-piperidin-1-ylbut-2-enamide
Formula: C31H32ClFN6O3
Similarity: 0.6641221374045801
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-[3-Chloro-4-(6-methylpyridin-3-yl)oxyanilino]-7-ethoxyquinazolin-6-yl]-2-fluoro-4-piperidin-1-ylbut-2-enamide
Formula: C31H32ClFN6O3
Similarity: 0.6641221374045801
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]-4-(1-oxidothiomorpholin-1-ium-4-yl)but-2-enamide
Formula: C23H23ClFN5O3S
Similarity: 0.6581196581196581
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(1-piperidyl)but-2-enamide
Formula: C27H29ClFN5O3
Similarity: 0.6532258064516129
Relative Targets: Epidermal growth factor receptor |
Name: N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]prop-2-enamide
Formula: C18H14ClFN4O2
Similarity: 0.6346153846153846
Relative Targets: Epidermal growth factor receptor |
Name: (E)-N-[4-(3-chloro-4-fluoro-anilino)pyrido[3,4-d]pyrimidin-6-yl]-4-(1-piperidyl)but-2-enamide
Formula: C22H22ClFN6O
Similarity: 0.6260869565217392
Relative Targets: Epidermal growth factor receptor | Receptor tyrosine-protein kinase erbB-2 | Receptor tyrosine-protein kinase erbB-4 |
Name: (E)-N-[4-(3-ethynylanilino)-7-methoxy-quinazolin-6-yl]-4-(1-piperidyl)but-2-enamide
Formula: C26H27N5O2
Similarity: 0.6218487394957983
Relative Targets: Epidermal growth factor receptor |
Name: (Z)-N-[4-(3-Chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide
Formula: C24H24ClF2N5O3
Similarity: 0.6198347107438017
Relative Targets: Epidermal growth factor receptor | Potassium voltage-gated channel subfamily H member 2 |
Name: (E)-N-[4-(3-Chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide
Formula: C24H24ClF2N5O3
Similarity: 0.6198347107438017
Relative Targets: Epidermal growth factor receptor | Potassium voltage-gated channel subfamily H member 2 |