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Approved Drugs
Inhibitors
Name:  (E)-N-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-2-fluoro-4-morpholin-4-ylbut-2-enamide
Formula:  C23H22ClF2N5O3
Similarity:  1.0
Relative Targets:   Epidermal growth factor receptor  |
Name:  (Z)-N-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-2-fluoro-4-piperidin-1-ylbut-2-enamide
Formula:  C24H24ClF2N5O2
Similarity:  0.8301886792452831
Relative Targets:   Epidermal growth factor receptor  | Potassium voltage-gated channel subfamily H member 2  |
Name:  (E)-N-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-2-fluoro-4-piperidin-1-ylbut-2-enamide
Formula:  C24H24ClF2N5O2
Similarity:  0.8301886792452831
Relative Targets:   Epidermal growth factor receptor  |
Name:  (Z)-N-[4-(3-Chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-2-fluoro-4-morpholin-4-ylbut-2-enamide
Formula:  C26H26ClF2N5O4
Similarity:  0.8
Relative Targets:   Epidermal growth factor receptor  | Potassium voltage-gated channel subfamily H member 2  |
Name:  (E)-N-[4-(3-Chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-2-fluoro-4-morpholin-4-ylbut-2-enamide
Formula:  C26H26ClF2N5O4
Similarity:  0.8
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-(3-morpholinopropoxy)quinazolin-6-yl]-2-methyl-prop-2-enamide
Formula:  C25H27ClFN5O3
Similarity:  0.7130434782608696
Relative Targets:   Epidermal growth factor receptor  |
Name:  (Z)-N-[4-(3-Chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-2-fluoro-4-piperidin-1-ylbut-2-enamide
Formula:  C27H28ClF2N5O3
Similarity:  0.7107438016528925
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-Chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-2-fluoro-4-piperidin-1-ylbut-2-enamide
Formula:  C27H28ClF2N5O3
Similarity:  0.7107438016528925
Relative Targets:   Epidermal growth factor receptor  |
Name:  (Z)-N-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide
Formula:  C21H20ClF2N5O2
Similarity:  0.7102803738317757
Relative Targets:   Tyrosine-protein kinase JAK2  | Epidermal growth factor receptor  | Hepatocyte growth factor receptor  | Platelet-derived growth factor receptor alpha  | Fibroblast growth factor receptor 2  | RAC-beta serine/threonine-protein kinase  | Potassium voltage-gated channel subfamily H member 2  | Receptor tyrosine-protein kinase erbB-4  |
Name:  Canertinib
Formula:  C24H25ClFN5O3
Similarity:  0.6810344827586207
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Dipeptidyl peptidase 1  | Receptor tyrosine-protein kinase erbB-4  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-(3-morpholinopropoxy)quinazolin-6-yl]but-2-enamide
Formula:  C25H27ClFN5O3
Similarity:  0.6779661016949152
Relative Targets:   Epidermal growth factor receptor  |
Name:  Dacomitinib
Formula:  C24H25ClFN5O2
Similarity:  0.6695652173913044
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Receptor tyrosine-protein kinase erbB-4  |
Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-(3-morpholinopropoxy)quinazolin-6-yl]prop-2-enamide;dihydrochloride
Formula:  C24H27Cl3FN5O3
Similarity:  0.6694915254237288
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Receptor tyrosine-protein kinase erbB-4  |
Name:  (Z)-N-[4-(3-Chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide
Formula:  C24H24ClF2N5O3
Similarity:  0.6610169491525424
Relative Targets:   Epidermal growth factor receptor  | Potassium voltage-gated channel subfamily H member 2  |
Name:  (E)-N-[4-(3-Chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)-2-fluorobut-2-enamide
Formula:  C24H24ClF2N5O3
Similarity:  0.6610169491525424
Relative Targets:   Epidermal growth factor receptor  | Potassium voltage-gated channel subfamily H member 2  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]-4-(1-oxidothiomorpholin-1-ium-4-yl)but-2-enamide
Formula:  C23H23ClFN5O3S
Similarity:  0.6581196581196581
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]prop-2-enamide
Formula:  C18H14ClFN4O2
Similarity:  0.6346153846153846
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-methoxy-6-quinolyl]-4-morpholino-but-2-enamide
Formula:  C25H23ClFN5O3
Similarity:  0.628099173553719
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)pyrido[3,4-d]pyrimidin-6-yl]-4-morpholino-but-2-enamide
Formula:  C21H20ClFN6O2
Similarity:  0.6260869565217392
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Receptor tyrosine-protein kinase erbB-4  |