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Approved Drugs
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Inhibitors
Name:  N-[3-[[2-[4-(4-acetylpiperazin-1-yl)-3-methoxy-anilino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]phenyl]prop-2-enamide
Formula:  C27H28F3N7O3
Similarity:  0.8360655737704918
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[2-[4-(4-acetylpiperazin-1-yl)-2-methoxy-anilino]-5-(trifluoromethyl)pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C27H27F3N6O4
Similarity:  0.8211382113821138
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide
Formula:  C25H28ClN7O2
Similarity:  0.7235772357723578
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[2-[2-methoxy-4-(4-morpholino-1-piperidyl)anilino]-5-(trifluoromethyl)pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide
Formula:  C31H35F3N8O4
Similarity:  0.6758620689655173
Relative Targets:   Epidermal growth factor receptor  |
Name:  2-[3-[[2-[4-(4-acetylpiperazin-1-yl)-2-methoxy-anilino]-5-chloro-pyrimidin-4-yl]amino]anilino]ethanesulfonyl fluoride
Formula:  C25H29ClFN7O4S
Similarity:  0.6567164179104478
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[2-[4-(4-acetylpiperazin-1-yl)-2-methoxy-anilino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide
Formula:  C30H31N7O4
Similarity:  0.6474820143884892
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  Jak3-IN-1
Formula:  C26H30ClN7O2
Similarity:  0.6287878787878788
Relative Targets:   Serine/threonine-protein kinase Sgk1  | Epidermal growth factor receptor  | Platelet-derived growth factor receptor beta  | Tyrosine-protein kinase JAK1  | Non-receptor tyrosine-protein kinase TYK2  | Dual specificity protein kinase TTK  | Receptor-type tyrosine-protein kinase FLT3  | Tyrosine-protein kinase Blk  | Tyrosine-protein kinase JAK3  | Focal adhesion kinase 1  | Tyrosine-protein kinase BTK  | Tyrosine-protein kinase ITK/TSK  | Receptor tyrosine-protein kinase erbB-4  |
Name:  N-[3-[[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide
Formula:  C26H30N8O3
Similarity:  0.6268656716417911
Relative Targets:   Epidermal growth factor receptor  |
Name:  2-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]-2-methyl-N-[3-(prop-2-enoylamino)phenyl]propanamide
Formula:  C29H35N7O3
Similarity:  0.6204379562043796
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]-methyl-carbamoyl]amino]phenyl]prop-2-enamide
Formula:  C27H32N8O3
Similarity:  0.6176470588235294
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-chloro-2-[4-(4-methylpiperazin-1-yl)-2-(trifluoromethyl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C25H24ClF3N6O2
Similarity:  0.6119402985074627
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[6-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-3-(trifluoromethyl)-2-pyridyl]oxy]phenyl]prop-2-enamide
Formula:  C27H28F3N5O3
Similarity:  0.6102941176470589
Relative Targets:   Dipeptidyl peptidase 1  |
Name:  WZ4002
Formula:  C25H27ClN6O3
Similarity:  0.6060606060606061
Relative Targets:   Epidermal growth factor receptor  | Dipeptidyl peptidase 1  |
Name:  N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]sulfanylphenyl]prop-2-enamide
Formula:  C25H27ClN6O2S
Similarity:  0.6060606060606061
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[2-[4-[4-(2-fluoroethyl)piperazin-1-yl]-2-methoxy-anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide
Formula:  C27H31FN8O3
Similarity:  0.6
Relative Targets:   Epidermal growth factor receptor  |
Name:  (4-fluorophenyl) 3-[[2-[4-(4-acetylpiperazin-1-yl)-2-methoxy-anilino]-5-chloro-pyrimidin-4-yl]amino]benzoate
Formula:  C30H28ClFN6O4
Similarity:  0.589041095890411
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[2-[2-Methoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxopyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide
Formula:  C28H29N7O3
Similarity:  0.5785714285714286
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide
Formula:  C27H28N8O3
Similarity:  0.5785714285714286
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[2-[4-(4-methylpiperazin-1-yl)anilino]-5-(trifluoromethyl)pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C25H25F3N6O2
Similarity:  0.5735294117647058
Relative Targets:   Epidermal growth factor receptor  |