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Approved Drugs

Name:  Olmutinib

Formula:  C26H26N6O2S

Similarity:  0.6031746031746031

Inhibitors

Name:  (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-3-cyclopropylprop-2-enamide

Formula:  C28H31ClN6O3

Similarity:  0.8333333333333334

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxy-5-fluoro-phenyl]prop-2-enamide

Formula:  C25H26ClFN6O3

Similarity:  0.8198198198198198

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[3-chloro-6-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-2-pyridyl]oxy]phenyl]prop-2-enamide

Formula:  C26H28ClN5O3

Similarity:  0.8181818181818182

Relative Targets:   Dipeptidyl peptidase 1  |

Name:  N-[3-[5-chloro-2-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)-1-piperidyl]anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C30H36ClN7O3

Similarity:  0.8166666666666667

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-(2-methoxy-4-morpholino-anilino)pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C24H24ClN5O4

Similarity:  0.8165137614678899

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazine-1-carbonyl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C26H27ClN6O4

Similarity:  0.8141592920353983

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-[4-(4-methylpiperazin-1-yl)-2-(trifluoromethyl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C25H24ClF3N6O2

Similarity:  0.8053097345132744

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-[4-(4-hydroxy-1-piperidyl)-2-methoxy-anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C25H26ClN5O4

Similarity:  0.8018018018018018

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]sulfanylphenyl]prop-2-enamide

Formula:  C25H27ClN6O2S

Similarity:  0.8018018018018018

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide

Formula:  C25H28ClN7O2

Similarity:  0.8018018018018018

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[2-chloro-3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxy-phenyl]prop-2-enamide

Formula:  C25H26Cl2N6O3

Similarity:  0.7876106194690266

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxy-2-fluoro-phenyl]prop-2-enamide

Formula:  C25H26ClFN6O3

Similarity:  0.7876106194690266

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-4-methylpent-2-enamide

Formula:  C29H32ClN7O3

Similarity:  0.775

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C24H25ClN6O2

Similarity:  0.7727272727272727

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-chloro-2-[2-methoxy-4-(1-methyl-4-piperidyl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C26H28ClN5O3

Similarity:  0.7699115044247787

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-cyclopropylprop-2-enamide

Formula:  C29H30ClN7O3

Similarity:  0.768595041322314

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-2-cyano-N-(2-hydroxy-1,1-dimethyl-ethyl)-3-[3-(3,4,5-trimethoxyphenyl)-1H-indazol-5-yl]prop-2-enamide

Formula:  C29H30ClN7O3

Similarity:  0.768595041322314

Relative Targets:   Ribosomal protein S6 kinase alpha-3  |

Name:  (E)-N-[3-[5-Chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-4,4-dimethylpent-2-enamide

Formula:  C30H34ClN7O3

Similarity:  0.7622950819672131

Relative Targets:   Epidermal growth factor receptor  |